Vagus nerve stimulation in the treatment of epilepsy
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چکیده
منابع مشابه
Vagus nerve stimulation in the treatment of epilepsy.
Vagus-nerve stimulation (VNS) is now an accepted treatment for patients with refractory epilepsy. There have been many studies suggesting that VNS affects the brain in such areas as the thalamus and other limbic structures. In addition, there is some evidence that norepinephrine is important in the prophylactic antiseizure effects of VNS. The efficacy of VNS has been established for partial sei...
متن کاملTreatment of epilepsy by stimulation of the vagus nerve.
We treated 14 patients with medically refractory partial seizures by stimulation of the vagus nerve in two single-blind pilot studies. Patients received stimulation through an implantable, programmable NeuroCybernetic Prosthesis, consisting of a pulse generator and a lead-electrode assembly. The mean reduction in seizure frequency after 14 to 35 months of vagal stimulation was 46.6%. Of the 14 ...
متن کاملVagus nerve stimulation for treatment of epilepsy in Rett syndrome.
This case series presents the outcomes of seven females with Rett syndrome and medically refractory epilepsy who were treated with adjunctive vagus nerve stimulation (VNS) therapy for a minimum of 12 months. Patients ranged in age from 1 to 14 years (median age 9 y) at the time of implantation, had experienced seizures for a median period of approximately 6 years, and had failed at least two tr...
متن کاملVagus nerve stimulation in the treatment of nervous system disease: a review article
The vagus nerve (VN), the longest cranial nerve and an essential part of the parasympathetic system, connects the central nervous system to respiratory, cardiovascular, immune, gastrointestinal, and endocrine systems and is involved in the maintenance of homeostasis by controlling these systems. Vagus nerve stimulation (VNS) is related to any method that would stimulate the vagal nerve via elec...
متن کاملAssessment of Vagus Nerve Stimulation for Epilepsy
Introduction and methodology. Despite a recent surge in availability of new antiepileptic medications and advances in surgical therapy for epilepsy, intractable epilepsy remains a very significant problem. At least 25 to 50% of patients with epilepsy suffer from breakthrough seizures or debilitating side effects of medications. We need a safe and effective treatment for these people, even if it...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2004
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.1041039